Preimplantation Genetic Testing (PGT)

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What is Preimplantation Genetic Testing (PGT)?

Preimplantation Genetic Testing (PGT) is a reproductive technology used to screen embryos for genetic abnormalities before they are implanted into the uterus during an in vitro fertilization (IVF) cycle. PGT allows couples undergoing IVF to increase the chances of a successful pregnancy by selecting embryos that do not carry specific genetic disorders or abnormalities.

When to go for Preimplantation Genetic Testing (PGT) testing?

Preimplantation Genetic Testing (PGT) is a technique used to identify genetic defects in embryos created through in vitro fertilization (IVF) before implantation in the uterus. PGT can help ensure that only healthy embryos are selected for transfer.

You should consult a doctor if:

  • Family History of Genetic Disorders: If you or your partner have a family history of genetic conditions or inherited disorders, PGT can help identify potential risks.
  • Recurrent Pregnancy Loss: If you have experienced multiple miscarriages, it may be beneficial to investigate potential genetic causes.
  • Advanced Maternal Age: Women over the age of 35 may have an increased risk of chromosomal abnormalities in embryos. PGT can help identify healthy embryos.
  • Infertility Issues: If you have had difficulty conceiving after multiple attempts or have undergone several IVF cycles without success, PGT may be a suitable option to enhance the chances of a successful pregnancy.
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Causes
  • Advanced Maternal Age
  • Known Genetic Disorders
  • Repeated IVF Failures
  • Recurrent Miscarriages
  • Previous Children with Genetic Disorders
Symptoms
  • Infertility
  • Miscarriages
  • Family History of Genetic Disorders
  • Abnormal Prenatal Testing Results
  • Age-Related Risks
Frequently Asked Questions

Risks include potential damage to embryos during the biopsy process, the possibility of inaccurate results (false positives or negatives), and ethical considerations regarding embryo selection.

Yes, PGT can determine the sex of an embryo, which can be useful for couples at risk of sex-linked genetic disorders. However, ethical considerations often surround this practice.

PGT is generally considered highly accurate, but it is not infallible. False positives or negatives can occur, so it's important to discuss results thoroughly with a genetic counselor.